Clinical and Radiographic Evaluation of Non-Surgical Therapy With and Without Ozone Gel Application in Controlled Type 2 Diabetic Patients With Periodontitis

• Status: Recruiting
• Trial end date: 2023-08-02
• Target enrollment: 0
• Participant gender: All

Summary

The adjunctive topical subgingival application ozone gel creates a great improvements in the clinical, bacteriological and immunological parameters over the gold standard of periodontal pocket treatment alone.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University

Criteria

Inclusion Criteria:

1. Patient with controlled diabetic type II. (HgA1C <7) (Mori et al., 2021)

2. Adult patients above 18 years old.

3. Patients with stage III and grade B periodontitis.

4. Patients accept 3-months follow-up period (cooperative patients).

5. Patients provide an informed consent

Exclusion Criteria:

• 1. Presence of prosthetic crowns. 2. Extensive restorations. 3. Periodontal therapy within the last 12 months. 4. Having surgical therapy or undergoing orthodontic treatment. 5. Ongoing drug therapy that might have an impact on the clinical signs and symptoms of periodontitis.

6. The use of antibiotics or anti-inflammatory drugs 1 month prior to the procedure and till the end of 3 months of follow-up.

7. Smokers. 8. Pregnant females. 9. Any known allergies