Clofarabine Plus Low-Dose Cytarabine for Patients With Higher-Risk Myelodysplastic Syndrome (MDS)
Status:
Completed
Trial end date:
2017-01-29
Target enrollment:
Participant gender:
Summary
The goal of this clinical research study is to learn if clofarabine when given in combination
with cytarabine can help to control myelodysplastic syndrome (MDS) after the disease could
not be controlled with standard therapy. The safety of this treatment will also be studied.
Clofarabine is designed to interfere with the growth and development of cancer cells.
Cytarabine is designed to insert itself into DNA (the genetic material of cells) of cancer
cells and stop the DNA from repairing itself.