Clomiphene Citrate, Estradiol and Sildenafil for Induction of Ovulation in Unexplained Infertility

• Status: Completed
• Trial end date: 2018-04-30
• Target enrollment: 0
• Participant gender: Female

Summary

Diagnosis of unexplained infertility is made after the recommended testing fails to reveal any abnormality. The treatment for unexplained infertility is empiric because it does not address a specific defect or functional impairment. The principal treatments for unexplained infertility include expectant observation with timed intercourse and lifestyle changes, clomiphene citrate and intrauterine insemination (IUI), controlled ovarian hyperstimulation (COH) with IUI, and IVF).

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Nesreen Abdel Fattah Abdullah Shehata
• Collaborator: Beni-Suef University
• Treatments: Citric Acid; Clomiphene; Enclomiphene; Estradiol; Estradiol 17 beta-cypionate; Estradiol 3-benzoate; Estradiol valerate; Ethinyl Estradiol; Polyestradiol phosphate; Sildenafil Citrate; Zuclomiphene

Criteria

Inclusion Criteria:

• Women whose infertility tests were normal then diagnosed as unexplained infertility.

Exclusion Criteria:

• Any cause of infertility male factor, tubal or ovarian.

• Chronic illness as cardiac or renal disease

• Any contraindication for used drugs