Clomiphene Citrate Plus uFSH Versus Aromatase Inhibitor Plus uFSH in Clomiphene Resistant Infertile PCOS Women

• Status: Unknown status
• Trial end date: 2014-09-01
• Target enrollment: 0
• Participant gender: Female

Summary

Polycystic ovarian syndrome (PCOS) is a condition characterized by infertility, infrequent periods and amenorrhea or irregular bleeding plus anovulatory infertility. Clomid is the standard first drug of treatment for ovulation induction. Ovulation and conception will occur in approximately 75 and 30 percent of cases respectively. Cases not ovulating in response to doses of clomid up to 150 mg/day are known as clomid resistant PCOS.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mansoura Integrated Fertility Center
• Treatments: Aromatase Inhibitors; Citric Acid; Clomiphene; Enclomiphene; Zuclomiphene

Criteria

Inclusion Criteria:

• CC resistant PCOS

• Infertile

• Females

• Age 18-38

Exclusion Criteria:

• Hyperprolactinaemia

• Cushing syndrome

• Adult onset adrenal hyperplasia

• Age > 38

• Other infertility factors in the couple than PCOS: male factor,tubal factor,edometriosis