Clonidine for Infra-orbital Nerve Block During Pediatric Cleft Lip Revision Surgeries

• Status: Not yet recruiting
• Trial end date: 2025-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Pain in children is usually an undertreated entity. Undertreating perioperative pain could lead to various metabolic, physiologic, and neurophysiological responses. The usual means of management i.e., opioids may increase the incidence of respiratory depression in this age group. Adequate postoperative analgesia in children is a vital part of perioperative care. Good pain relief minimizes oxygen requirement, reduces cardio-respiratory demands, and promotes early ambulation and recovery. Regional block given preoperatively in combination with general anesthesia provides good preemptive analgesia. It is associated with hemodynamic stability, rapid and complete recovery, and reduced analgesic requirement in postoperative period.

Type of the study: A prospective randomized controlled double-blind study.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Bupivacaine; Clonidine

Criteria

Inclusion Criteria:

• Age: 1-7 years old.

• Gender: both.

• ASA physical status I-II

• Children scheduled to undergo cleft lip revision surgeries.

Exclusion Criteria:

• History of developmental delay or mental retardation, which will make observational pain intensity assessment difficult.

• Parents refusal.

• Hypersensitivity to any local anesthetics.

• Bleeding diathesis.

• Children with co-morbid conditions like congenital heart disease, respiratory pathology and central nervous system disorders.

• Skin lesions or wounds at the puncture site of the proposed block.