Clopidogrel Resistance and the Possibility of Its Affection

• Status: Temporarily not available
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to determine, whether the resistance to clopidogrel could be affected by higher doses of this drug, or by replacement of clopidogrel with another ADP-antagonist ticlopidine.

Details

• Lead Sponsor: Charles University, Czech Republic
• Treatments: Clopidogrel; Ticlopidine

Criteria

Inclusion Criteria:

• written informed consent

• coronary artery disease verified by coronary angiography

• percutaneous coronary intervention with stent implantation

• standard indication for dual antiplatelet therapy

Exclusion Criteria:

• scheduled surgical revascularization by aortocoronary bypass

• insufficient cooperation of the patient

• coagulopathy in history with a higher risk of bleeding

• life expectancy shorter than 1 year

• severe anemia with hemoglobin level< 10,0 g/dl

• platelet count < 100,000)