Closed-loop Control of Glucose Levels (Artificial Pancreas) for 12 Days in Adults With Type 1 Diabetes
Status:
Completed
Trial end date:
2020-01-27
Target enrollment:
Participant gender:
Summary
Closed-loop strategy is composed of three components: glucose sensor to read glucose levels,
insulin pump to infuse insulin and a dosing mathematical algorithm to decide on the required
insulin dosages based on the sensor's readings.
The objective of this study is to compare the effectiveness of single-hormone closed-loop and
sensor-augmented pump therapy in regulating day-and-night glucose levels in adults with T1D
for 12 days in outpatient settings.
The investigators hypothesize that dual-hormone closed-loop will increase the percentage of
time of glucose levels spent in the target range in adults compared to single-hormone
closed-loop, which in turn will be more effective than sensor-augmented pump therapy.