Overview

Closed-loop Control of Glucose Levels (Artificial Pancreas) for 5 Days in Adults With Type 1 Diabetes

Status:
Withdrawn
Trial end date:
2018-11-01
Target enrollment:
Participant gender:
Summary
Closed-loop strategy is composed of three components: glucose sensor to read glucose levels, insulin pump to infuse insulin and a dosing mathematical algorithm to decide on the required insulin dosages based on the sensor's readings. The main objective of this project is to compare the efficacy of single-hormone closed-loop strategy and sensor-augmented pump therapy to regulate glucose levels in outpatient settings for 5 consecutive days in adults with type 1 diabetes. The investigators hypothesized that single-hormone closed-loop strategy will increase the time spent in the target range compared to sensor-augmented pump therapy.
Phase:
Phase 2
Details
Lead Sponsor:
Institut de Recherches Cliniques de Montreal
Treatments:
Glucagon
Glucagon-Like Peptide 1
Hormones
Insulin
Insulin, Globin Zinc