Overview

Co-Administration of MK-4618 With Antihypertensive Agents (MK-4618-010)

Status:
Completed
Trial end date:
2011-11-01
Target enrollment:
Participant gender:
Summary
This study will evaluate the safety and tolerability of MK-4618 when coadministered with antihypertensive agents and will evaluate changes in blood pressure following co-administration of MK-4618 with a beta blocker and a vasodilator. The primary hypothesis of the study is that MK-4618 does not result in a clinically meaningful change in systolic blood pressure relative to placebo when co-administered with a beta-blocker or with amlodipine.
Phase:
Phase 1
Details
Lead Sponsor:
Merck Sharp & Dohme Corp.
Treatments:
Amlodipine
Antihypertensive Agents
Metoprolol