Overview

Coadministration of GA2 Sporozoites With Adjuvants

Status:
Not yet recruiting
Trial end date:
2023-11-01
Target enrollment:
Participant gender:
Summary
This study will assess the coadministration of genetically attenuated Plasmodium falciparum ∆mei2 (GA2) sporozoites with adjuvants (BCG and YF-17D vaccination and imiquimod cream). Primary outcomes will be safety, tolerability and protective efficacy against CHMI.
Phase:
Early Phase 1
Details
Lead Sponsor:
Leiden University Medical Center
Treatments:
Imiquimod