Coenzyme Q10 in Older Athletes Treated With Statin Medications

• Status: Completed
• Trial end date: 2011-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the effect of coenzyme Q10 administration in improving mitochondrial function as measured by anaerobic threshold in older athletes on a stable dose of statin medication.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Richard Deichmann, MD
• Treatments: Coenzyme Q10; Ubiquinone

Criteria

Inclusion Criteria:

• Patients ≥ 50 years of age, male or female.

• Patients on a stable dose of statin medication for at least 3 months prior to enrollment in the study

• Self-Described Athletes with any of the following characteristics:

• Participation in a competitive athletic event within the past year or currently training for a competitive athletic event within the 6 months following enrollment

• Regular exercise activity of at least 45 minutes duration 5 times per week

Exclusion Criteria:

• Use of coenzyme Q10 during the preceding two months.

• CPK level at baseline greater than two times the upper limits of normal

• LDL level at baseline greater than 160 for those without a cardiovascular risk or cardiovascular risk equivalent

• LDL level at baseline greater than 130 for those with a cardiovascular risk or cardiovascular risk equivalent