Overview

Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab

Status:
Not yet recruiting
Trial end date:
2027-09-07
Target enrollment:
Participant gender:
Summary
This study is a mechanistic randomized controlled trial that investigates whether inhibition of tumor necrosis factor signaling via intravenous infusion of infliximab improves psychomotor speed and executive functioning in depressed individuals who exhibit an inflammatory phenotype.
Phase:
Phase 2
Details
Lead Sponsor:
Massachusetts General Hospital
Treatments:
Infliximab