Cognitive Impairment Following Sedation for Colonoscopy With Propofol, Midazolam and Fentanyl Combinations
Status:
Completed
Trial end date:
2008-02-01
Target enrollment:
Participant gender:
Summary
Our hypothesis is that adding midazolam and/or fentanyl to propofol sedation for elective
outpatient colonoscopy increases cognitive impairment at hospital discharge without improving
intraoperative conditions or reducing intraoperative side-effects.
200 healthy patients aged 18 years or older will be randomised to receive propofol or
propofol plus midazolam and/or fentanyl. Cognitive impairment will be tested at hospital
discharge using Cogstate computerised testing software.