Overview

Cognitive Impairment Related to Atrial Fibrillation Prevention Trial

Status:
Completed
Trial end date:
2021-03-09
Target enrollment:
Participant gender:
Summary
Cognitive and functional decline observed in atrial fibrillation (AF) patients are related to thrombotic and/or cardioembolic events. Use of warfarin for the prevention of stroke in AF patients, despite effective, remains beyond desired levels because of interactions with food and fluctuations in blood levels. Because of a more stable anticoagulation state, Dabigatran may offer better protection against thrombotic phenomenon and, consequently, mitigate the process of cognitive and functional compromise.
Phase:
Phase 4
Details
Lead Sponsor:
University of Sao Paulo
Collaborators:
Boehringer Ingelheim
Federal University of Minas Gerais
Treatments:
Dabigatran
Warfarin