Cognitive Recovery After Electroconvulsive Therapy and General Anesthesia

• Status: Completed
• Trial end date: 2019-09-11
• Target enrollment: 0
• Participant gender: All

Summary

This study is geared toward characterizing the recovery of brain activity and cognitive function following treatments of electroconvulsive therapy and ketamine general anesthesia.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Washington University School of Medicine
• Collaborator: James S McDonnell Foundation
• Treatments: Anesthetics; Etomidate; Ketamine

Criteria

Inclusion Criteria:

• Treatment resistant depression requiring outpatient ECT

• Planned right unilateral ECT stimulation

• English speaking

• Able to provide written informed consent

Exclusion Criteria:

• Known brain lesion or neurological illness that causes cognitive impairment

• Schizophrenia

• Schizoaffective disorder

• Blindness or deafness or motor impediments that may impair performance for cognitive testing battery

• Inadequate ECT seizure duration with etomidate