Colchicine Randomized Double-Blind Controlled Crossover Study in Behcet's Disease
Status:
Completed
Trial end date:
2006-05-01
Target enrollment:
Participant gender:
Summary
Colchicine was first used in Behcet's Disease (BD), in 1977. There are controversial reports
of the efficacy of Colchicine in BD. For some experts the unresponsiveness of some patients
could be explained by genetic difference between the Silk Road BD and sporadic BD from other
parts of the world.
To test this hypothesis (the inefficacy of colchicine in the Silk Road BD), we designed a
randomized double-blind controlled crossover study in Iran, which is in the middle of the
Silk Road, and has the second highest prevalence of BD in the world.