Colchine for the Stability of Coronary Plaque in Acute Coronary Syndrome(COLOCT)
Status:
Recruiting
Trial end date:
2023-06-30
Target enrollment:
Participant gender:
Summary
Evidence from the COLCOT Trial has shown that anti-inflammatory effect of colchicine reduced
the risk of cardiovascular events in patients with recent myocardial infarction. We
hypothesized that this might be due to the improvement of the coronary plaque stability by
colchicine. Optical coherence tomography (OCT) is the most precise method to detect plaque
stability in clinical practice. Thus, the purpose of this study is to evaluate the efficacy
and safety of colchicine on improving the stability of coronary plaque in patients with acute
coronary syndrome.