Collagen-thrombin Matrix Efficacy During Cardiac Surgery: a Prospective Randomized Controlled Trial
Status:
Completed
Trial end date:
2019-12-31
Target enrollment:
Participant gender:
Summary
In this prospective open-label randomized trial, 80 patients with elective off-pump coronary
artery bypass (OPCAB) surgery were enrolled. After primary suture of aortocoronary
anastomosis, if an area of hemorrhage was identified, patients were randomized to receive
Floseal® or Collastat® (n=40), respectively. The selected agent was applied with compression
of the target area for 1 min. If hemostasis was not achieved, the agent was re-applied for a
further 1 min, and was repeated up to 5 min, after which rescue treatment was applied,
including any conventional surgical methods.