Combination Antibiotic Therapy Compared to Monotherapy in the Treatment of Acute COPD
Status:
Completed
Trial end date:
2020-12-30
Target enrollment:
Participant gender:
Summary
The investigators hypothesized that the empirical use of fluoroquinolones together with
beta-lactam antibiotics will change their therapeutic success in patients with acute
exacerbations of COPD compared to that in patients in whom a single beta-lactam treatment was
used. The main goal of this study was to compare the clinical and bacterial success from the
use of a combination of beta-lactam and fluoroquinolone antibiotics with that of a single
beta-lactam treatment, in adult patients with COPD exacerbations.