Combination Chemotherapy Followed by Surgery and Peripheral Stem Cell or Bone Marrow Transplantation in Treating Infants With Newly Diagnosed Neuroblastoma

• Status: Completed
• Trial end date: 2009-03-01

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell or bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells.

PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy given before surgery followed by peripheral stem cell or bone marrow transplantation in treating infants who have newly diagnosed neuroblastoma.

• Phase: Phase 2

Details

• Lead Sponsor: European Infant Neuroblastoma Study Group - 1999
• Treatments: Busulfan; Carboplatin; Cyclophosphamide; Doxorubicin; Etoposide; Liposomal doxorubicin; Melphalan; Vincristine