Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma
Status:
Completed
Trial end date:
2008-06-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Combining more than one drug may kill more tumor cells.
Chemoprotective drugs such as dexrazoxane may protect normal cells from the side effects of
chemotherapy.
PURPOSE: Phase III trial to study the effectiveness of three combination chemotherapy
regimens plus dexrazoxane in treating patients who have newly diagnosed nonmetastatic
osteosarcoma.