Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors
Status:
Completed
Trial end date:
2011-12-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Combining more than one drug may kill more tumor cells. Inserting a
specific gene into a person's peripheral stem cells may improve the body's ability to fight
cancer or make the cancer more sensitive to chemotherapy.
PURPOSE: Phase I trial to study the effectiveness of combination chemotherapy plus gene
therapy in treating patients who have CNS tumors.
Phase:
Phase 1
Details
Lead Sponsor:
Indiana University
Collaborator:
Indiana University Melvin and Bren Simon Cancer Center