Combination Chemotherapy Plus PSC-833 in Treating Children With Refractory or Relapsed Acute Leukemia
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Phase I trial to study the effectiveness of PSC-833 plus etoposide and mitoxantrone in
treating children who have refractory or relapsed acute leukemia. Drugs used in chemotherapy
use different ways to stop cancer cells from dividing so they stop growing or die. Some
cancers become resistant to chemotherapy drugs. Combining PSC-833 with chemotherapy may
reduce resistance to the drug and allow more cancer cells to be killed.