Combination Chemotherapy With or Without Celecoxib in Treating Patients With Metastatic Colorectal Cancer
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy such as irinotecan, capecitabine, leucovorin, and
fluorouracil use different ways to stop tumor cells from dividing so they stop growing or
die. Celecoxib may stop the growth of colorectal cancer by stopping blood flow to the tumor.
It is not yet known which combination chemotherapy regimen with or without celecoxib is more
effective in treating metastatic colorectal cancer.
PURPOSE: This randomized phase III trial is studying two combination chemotherapy regimens
and celecoxib to see how well they work compared to two combination chemotherapy regimens
alone in treating patients with metastatic colorectal cancer.
Phase:
Phase 3
Details
Lead Sponsor:
European Organisation for Research and Treatment of Cancer - EORTC