Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia

• Status: Completed
• Trial end date: 1969-12-31

Summary

This phase II trial is studying how well combination chemotherapy with or without donor peripheral stem cell transplant works in treating children with acute lymphoblastic leukemia. Giving combination chemotherapy before a donor peripheral stem cell transplant helps stop the growth of cancer cells. It also helps stop the patient's immune system from rejecting the donor's stem cells. When the healthy stem cells from a donor are infused into the patient they may help the patient's bone marrow make stem cells, red blood cells, white blood cells, and platelets.

• Phase: Phase 3

Details

• Lead Sponsor: National Cancer Institute (NCI)
• Treatments: 6-Mercaptopurine; Asparaginase; Cyclophosphamide; Cyclosporine; Cyclosporins; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Etoposide phosphate; Ifosfamide; Imatinib Mesylate; Leucovorin; Levoleucovorin; Mercaptopurine; Methotrexate; Pegaspargase; Vincristine