Combination Chemotherapy and Oblimersen in Treating Patients With Advanced Colorectal Cancer
Status:
Completed
Trial end date:
2004-10-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Combining more than one drug may kill more tumor cells. Oblimersen
may increase the effectiveness of chemotherapy by making tumor cells more sensitive to the
drugs.
PURPOSE: Phase I/II trial to study the effectiveness of combining oxaliplatin, fluorouracil,
and leucovorin with oblimersen in treating patients who have unresectable, metastatic, or
recurrent colorectal cancer.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
The University of Texas Health Science Center at San Antonio