Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain
Status:
Completed
Trial end date:
2006-12-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as carboplatin, etoposide, ifosfamide, and
cisplatin, work in different ways to stop the growth of tumor cells, either by killing the
cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill
tumor cells. Giving more than one drug (combination chemotherapy) with radiation therapy may
kill more tumor cells.
PURPOSE: This phase III trial is studying combination chemotherapy followed by radiation
therapy to see how well it works compared to radiation therapy alone in treating patients
with germ cell tumors in the brain.