Combination Chemotherapy and Rituximab With Pegfilgrastim Followed by Rituximab, in Large B-Cell Non-Hodgkin's Lymphoma
Status:
Completed
Trial end date:
2010-02-01
Target enrollment:
Participant gender:
Summary
The purposes of this trial are to decrease toxicity and improve treatment effectiveness
elderly patients. With a short course of chemotherapy with cyclophosphamide, mitoxantrone,
vincristine, and prednisone with concurrent administration of rituximab it is likely to be as
effective as longer programs, and will certainly be better tolerated by this patient group.
The addition of maintenance therapy may result in substantial prolongation of remission
duration.