Combination Chemotherapy and Surgery With or Without G-CSF in Treating Patients With Osteosarcoma
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Colony-stimulating factors such as G-CSF may increase the number of
immune cells found in bone marrow or peripheral blood and may help a person's immune system
recover from the side effects of chemotherapy. It is not yet known whether chemotherapy and
surgery plus G-CSF is more effective than chemotherapy and surgery alone in treating patients
with osteosarcoma.
PURPOSE: Randomized phase III trial to compare the effectiveness combination chemotherapy and
surgery with or without G-CSF in treating patients who have newly diagnosed osteosarcoma.
Phase:
Phase 3
Details
Lead Sponsor:
European Organisation for Research and Treatment of Cancer - EORTC