Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor
Status:
Active, not recruiting
Trial end date:
2023-11-26
Target enrollment:
Participant gender:
Summary
This phase III trial studies how well combination chemotherapy and surgery work in treating
young patients with Wilms tumor. Drugs used in chemotherapy work in different ways to stop
the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by
stopping them from spreading. Giving more than one drug (combination chemotherapy) may kill
more tumor cells. Giving combination chemotherapy before surgery may make the tumor smaller
and reduce the amount of normal tissue that needs to be removed. Giving it after surgery may
kill any tumor cells that remain after surgery.