Combination Chemotherapy and Tipifarnib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
Status:
Terminated
Trial end date:
2008-01-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as cytarabine, daunorubicin, and etoposide, work
in different ways to stop the growth of cancer cells, either by killing the cells or by
stopping them from dividing. Tipifarnib may stop the growth of cancer cells by blocking some
of the enzymes needed for cell growth. Giving combination chemotherapy together with
tipifarnib may kill more cancer cells.
PURPOSE: This phase I trial is studying the side effects and best dose of tipifarnib when
given together with combination chemotherapy in treating patients with newly diagnosed acute
myeloid leukemia.