Combination Chemotherapy in Treating Pain in Hormone Refractory Metastatic Prostate Cancer
Status:
Completed
Trial end date:
2009-02-10
Target enrollment:
Participant gender:
Summary
RATIONALE: Some drugs used in chemotherapy can reduce the pain experienced by some people
with cancer. Combining more than one drug may be more effective at reducing cancer pain. It
is not known whether receiving combination chemotherapy with clodronate is more effective
than receiving combination chemotherapy without clodronate for hormone refractory metastatic
prostate cancer.
PURPOSE: Randomized double-blinded phase III trial to compare the effectiveness of
combination chemotherapy using mitoxantrone plus prednisone with or without clodronate in
treating pain in patients with hormone refractory metastatic prostate cancer.