Combination Chemotherapy in Treating Patients Undergoing Surgery for Newly Diagnosed High-Grade Osteosarcoma
Status:
Completed
Trial end date:
2008-01-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as ifosfamide, methotrexate, cisplatin, and
doxorubicin, work in different ways to stop the growth of tumor cells, either by killing the
cells or by stopping them from dividing. Giving chemotherapy before surgery may make the
tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving it
after surgery may kill any tumor cells that remain after surgery.
PURPOSE: This clinical trial is studying how well combination chemotherapy works in treating
patients undergoing surgery for newly diagnosed high-grade osteosarcoma.