Overview

Combination Chemotherapy in Treating Patients With Advanced Head and Neck Cancer

Status:
Completed
Trial end date:
2004-08-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known whether cisplatin plus fluorouracil are more effective than paclitaxel plus cisplatin in treating patients with advanced head and neck cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of two combination chemotherapy regimens in treating patients with advanced head and neck cancer.
Phase:
Phase 3
Details
Lead Sponsor:
Eastern Cooperative Oncology Group
Collaborators:
National Cancer Institute (NCI)
Southwest Oncology Group
Treatments:
Albumin-Bound Paclitaxel
Cisplatin
Fluorouracil
Paclitaxel