Overview

Combination Chemotherapy in Treating Patients With Stage III Colon Cancer

Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which chemotherapy regimen is more effective for stage III colon cancer. Randomized phase III trial to compare the effectiveness of fluorouracil plus leucovorin with or without irinotecan in treating patients who have undergone surgery for stage III colon cancer.
Phase:
Phase 3
Details
Lead Sponsor:
National Cancer Institute (NCI)
Collaborators:
Eastern Cooperative Oncology Group
NCIC Clinical Trials Group
North Central Cancer Treatment Group
Southwest Oncology Group
Treatments:
Calcium
Calcium, Dietary
Fluorouracil
Irinotecan
Leucovorin
Levoleucovorin