Overview

Combination Chemotherapy in Treating Young Patients With Langerhans Cell Histiocytosis

Status:
Completed
Trial end date:
2013-06-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of Langerhans cell histiocytosis, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may be an effective treatment for Langerhans cell histiocytosis. PURPOSE: This randomized clinical trial is studying combination chemotherapy to see how well it works in treating young patients with Langerhans cell histiocytosis.
Phase:
N/A
Details
Lead Sponsor:
Histiocyte Society
Treatments:
Calcium
Leucovorin
Levoleucovorin
Methotrexate
Prednisolone
Vinblastine