Overview
Combination Medications vs. Patch Alone for Medically-Ill Smokers
Status:
Completed
Completed
Trial end date:
2008-01-01
2008-01-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
Randomized clinical trial to evaluate a flexibly-dosed-3-medication combination for up to 6 months in smokers with medical illnessPhase:
Phase 4Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
University of Medicine and Dentistry of New JerseyCollaborators:
Robert Wood Johnson Foundation
Rutgers Cancer Institute of New JerseyTreatments:
Bupropion
Nicotine
Criteria
Inclusion Criteria:- currently smoking at least 10 cigarettes per day (confirmed by high exhaled
carbon-monoxide (CO))
- 18 years or older
- interested in quitting within the next 30 days
- one or more pre-defined medical illnesses (including cardiovascular disease, other
vascular disease, chronic pulmonary disease, cancer, hypertension, diabetes,
hyperlipidemia, and recurrent pulmonary infections)
Exclusion Criteria:
- contraindications to pharmacotherapy (including unstable angina, myocardial infarction
within 2 months, severe arrhythmia, seizure disorder, serious mental illness requiring
antipsychotic medications)
- current use of other tobacco products (smokeless tobacco, cigars, pipes, etc.),
bupropion, clonidine, nortriptyline, or nicotine replacement medications
- unable to give consent