Overview

Combination Pharmacological Interventions for Multiple Mechanisms of Obstructive Sleep Apnea

Status:
Recruiting
Trial end date:
2021-09-15
Target enrollment:
Participant gender:
Summary
Currently, there is no pharmacological intervention for OSA that targets multiple pathophysiological deficits in combination. Here the investigators study the effect on sleep apnea severity of combinations of pharmacological agents that stimulate the pharyngeal muscles, stabilize ventilatory control, and increase the arousal threshold.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Brigham and Women's Hospital
Collaborator:
Apnimed