Combination Therapy With Biofeedback, Loperamide and Stool Bulking Agents
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Background: Biofeedback and medical treatments have been extensively used for moderate fecal
incontinence. There is limited data comparing and combining these two treatments.
Aim: To evaluate the effect of biofeedback and medical treatments, separately and in
combination.
Methods: Sixty-five consecutive female patients, referred to a tertial center for fecal
incontinence were included. The patients were randomized to start with either biofeedback
(4-6 months) or medical treatment with loperamide and stool-bulking agents (2 months). Both
groups continued with a combination treatments, i.e. medical treatment was added to
biofeedback and vice versa. A two-week prospective bowel symptom diary and anorectal
physiology were evaluated at baseline, after single- and combination treatments.