Combined Agent Randomized Trial of Induction of Labor

• Status: Completed
• Trial end date: 2007-04-01
• Target enrollment: 0
• Participant gender: All

Summary

To compare sequential dinoprostone and oxytocin for induction of labor at term with intact membranes and an unripe cervix to two simultaneous regimens. Our aim was to confirm findings from smaller trials and add to data on fetal safety.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Weill Medical College of Cornell University
• Treatments: Dinoprostone; Oxytocin

Criteria

Inclusion Criteria:

• > or = to 36 weeks of gestation

• Singleton fetus

• Cephalic presentation

• Intact membranes and an unripe cervix (Bishop score <6)

Exclusion Criteria:

• Multifetal gestation

• Rupture of membranes

• Ripe cervix (Bishop score >6)

• Active labor

• Contraindication to vaginal delivery

• Previous uterine surgery

• Non-cephalic presentation

• Fetal macrosomia