Combined Colloids And Crystalloids Versus Crystalloids in Women With Preeclampsia Undergoing Cesarean Delivery

• Status: Completed
• Trial end date: 2021-07-15
• Target enrollment: 0
• Participant gender: Female

Summary

This study will compare between combination of colloids/crystalloids and crystalloids in women with preeclampsia undergoing elective cesarean delivery under spinal anesthesia

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mansoura University
• Treatments: Anesthetics; Bupivacaine; Ephedrine; Fentanyl; Oxytocin; Pseudoephedrine

Criteria

Inclusion Criteria:

• Preeclampsia: Blood Pressure ≥140/90 mmHg after 20 weeks' gestation and proteinuria ≥300 mg/24 hours or 1+ on urine dipstick

• Singleton pregnancy

• Elective cesarean delivery under spinal anesthesia

Exclusion Criteria:

• Height <150 cm

• Weight <60 kg

• Body mass index ≥45 kg/m2

• Women presenting in labor

• Contraindications to spinal anesthesia (increased intracranial pressure or local skin infection)

• Diabetes mellitus, cardiovascular, cerebrovascular, or renal disease

• Preoperative administration of intravenous hydralazine or magnesium sulphate

• Hemoglobin <10 gm/dL

• International Normalized Ratio >1.3

• Platelet count <100,000 /mm3

• Preoperative serum creatinine >1.1 mg/dL