Combined Pharmaco/Behavior Therapy in Adolescent Smokers
Status:
Completed
Trial end date:
2009-07-01
Target enrollment:
Participant gender:
Summary
In the current proposal, we intend to study the efficacy of bupropion SR with or without
combined contingency management (CM) among adolescent cigarette smokers. The proposed study
will test not only medication (bupropion SR), but also combination of medication and CM in
potentially improving smoking cessation outcomes AND retention of adolescent smokers in the
study.
Hypothesis to be tested: Bupropion SR treatment will increase abstinence from cigarette
smoking (as measured by urine cotinine and continuous abstinence) in adolescent smokers as
compared to treatment with placebo only.
Hypothesis to be tested: Adolescent smokers treated with combined bupropion SR + contingency
management (CM) treatment will have increased retention and increased abstinence rates when
compared to bupropion SR alone or CM + placebo treated groups (as measured by decreased
drop-out of participants, urine cotinine and continuous abstinence).
Hypothesis to be tested: CM will increase the abstinence from cigarette smoking (as measured
by urine cotinine and continuous abstinence) in adolescent smokers as compared to treatment
with placebo only.
Phase:
Phase 2
Details
Lead Sponsor:
Medical University of South Carolina
Collaborators:
National Institute on Drug Abuse (NIDA) National Institutes of Health (NIH)