Combined Therapy With L-Thyroxine and L-Triiodothyronine Compared to L-Thyroxine Alone

• Status: Completed
• Trial end date: 2004-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

The objective of this study was to analyze the features of monotherapy with L-T4 in comparison with combined therapy with L-T4 and L-T3 in patients with primary hypothyroidism.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: I.M. Sechenov First Moscow State Medical University

Criteria

Inclusion Criteria:

• Premenopausal women with overt primary hypothyroidism (reduced T4 concentration accompanied by increased TSH concentration at the time of initial diagnosis) who did not receive thyroid hormones

Exclusion Criteria:

• Peri- and postmenopause

• Pregnancy

• Major comorbidity

• Use of drugs that affect metabolism or bioavailability of thyroid hormones preparations.