Combined Vasopressin, Methylprednisolone, and Epinephrine for Inhospital Cardiac Arrest
Status:
Completed
Trial end date:
2007-04-01
Target enrollment:
Participant gender:
Summary
A randomized controlled trial did not show benefit of vasopressin versus epinephrine in
inhospital cardiac arrest. Preceding laboratory data suggest that combined vasopressin and
epinephrine ensure long-term survival and neurologic recovery. Also, postresuscitation
abnormalities mimic severe sepsis. The investigators hypothesized that combined vasopressin
and epinephrine during cardiopulmonary resuscitation (CPR), and steroid supplementation
during and after (when required) CPR may improve survival in cardiac arrest.