Combining Stellate Ganglion Block With Prolonged Exposure for PTSD
Status:
Not yet recruiting
Trial end date:
2026-08-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to compare the combination of Massed Prolonged Exposure
(Massed PE; a behavioral therapy for PTSD) and a stellate ganglion block (SGB; an injection
of a local anesthetic into the front of the neck) with Massed Prolonged Exposure and a sham
injection in a sample of military service members or retirees with PTSD. The main questions
it aims to answer are: (1) Does the addition of an SGB improve treatment outcomes associated
with Massed PE? and (2) Do differences in psychophysiological arousal during the exposure
portion of treatment help explain treatment outcomes for PTSD. Participants will receive ten
90-minute session of Massed PE. Between the first and second Massed PE sessions, half of the
participants will receive a SGB, and half will receive a sham SGB.
Phase:
Phase 2
Details
Lead Sponsor:
The University of Texas Health Science Center at San Antonio