Comparative Effectiveness Trial in the Treatment of Pediatric Plaque Morphea

• Status: Withdrawn
• Trial end date: 2017-05-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a study designed to evaluate the comparative effectiveness of topical medications for the treatment of circumscribed morphea.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medical College of Wisconsin
• Collaborators: Mayo Clinic; Seattle Children's Hospital; University of Toronto
• Treatments: Calcipotriene; Calcitriol; Clobetasol; Tacrolimus

Criteria

Inclusion Criteria:

• presence of at least 1 active lesion of morphea on the neck, trunk, or extremities with no prior treatment to that lesion for at least 4 weeks

Exclusion Criteria:

• children receiving phototherapy or systemic therapy for their morphea

• children with linear or generalized morphea

• lesions on the face

• greater than 3% body surface area involvement

• open or ulcerated skin within morphea lesions