Comparative Effectiveness of Cystine Versus Nicotine Replacement Therapy

• Status: Not yet recruiting
• Trial end date: 2022-12-01
• Target enrollment: 0
• Participant gender: All

Summary

A pragmatic, single blinded, randomized, controlled non-inferiority trial of Cytisine versus Nicotine Replacement Therapy for continuous abstinence is conducted in the government run primary health hospitals in Mongolia.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Loma Linda University
• Collaborators: Mongolian National University of Medical Sciences; Pfizer
• Treatments: Nicotine

Criteria

Inclusion Criteria:

• Seeking smoking cessation treatment

• Ages 18 years or older

• Currently smoking > 5 cigarettes per day

• Willingness to make quit attempt with pharmacotherapy

• Able to provide verbal and written informed consent

• Have telephone access

Exclusion Criteria:

• Pregnancy or currently breastfeeding

• Current users of NRT (patch, gum, lozenge)

• Current users of non_NRT smoking cessation pharmacotherapy

• Enrolled in another smoking cessation program (non-governmental)

• Clinical disorder that contraindicates use of NRT or Cytisine (heart attack, stroke, severe angina within the past 2 weeks, uncontrolled hypertension, phaeochromocytoma, severe mental illness)