Overview

Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study

Status:
RECRUITING
Trial end date:
2029-12-01
Target enrollment:
Participant gender:
Summary
This goal of this study is to compare three medications used for migraine preventive treatment. This study will compare atogepant, a newer migraine preventive medication, with two older preventive medications, topiramate and propranolol. It will be determined if one works better and is more tolerable than the others. Research participants will: * Be randomly assigned to one of the three medications. * Provide information about their migraine pattern using a daily headache diary and during research visits.
Phase:
PHASE4
Details
Lead Sponsor:
Mayo Clinic
Collaborators:
AbbVie
Patient-Centered Outcomes Research Institute
University of Iowa
Treatments:
atogepant
Propranolol
Topiramate