Comparative Effectiveness of Psoriasis Treatments on Systemic Inflammation
Status:
Completed
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
This is a prospective longitudinal observational pilot study of psoriasis patients on
continuous standard-of-care systemic therapeutics to determine the level of change in
established (plasma/serum) and investigative (cellular) biomarkers that are associated with
increased risk of CVD events.
The final endpoint of the proposed study will be a ranking of the examined biomarkers based
upon an integrated assessment of biomarker behavior over time.
Secondary outcomes will assess changes in coronary artery calcification scoring, PET-MRI,
skin biopsies, and clinical improvement.