Comparative Effects of Perindopril and Zofenopril on Blood Pressure Control and Oxidative Status Blacks Hypertensive Patients.

• Status: Completed
• Trial end date: 2019-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study is to compare the short term effect of perindopril and zofenopril in the management of hypertension and the oxydative stress in blacks hypertensive patients.

PEZO-HP is a double-arm, double-blind, randomized and parallel clinical trial conducted at the Yaoundé Central Hospital.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yaounde Central Hospital
• Treatments: Calcium; Captopril; Perindopril; Zofenopril

Criteria

Inclusion Criteria:

• Hypertensive patients

• On a stable atihypertensive therapies (determined by the investigator) for at least 3 months with no classes changes. The pharmacological treatment should not include an angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker

• Subject must not present any contraindication to exercise

• Before any study-specific procedure, the appropriate written informed consent must be obtained.

Exclusion Criteria:

• Side effects affecting life quality of patients (determined by the Data Safety Monitoring Board).

• Withdrawal of consent